ALSERepository of Iași University of Life Sciences, ROMANIA

Ascorbate-glutathion affiliation and the treatment of nutritional muscular dystrophy in lambs with special reference to the oxidative stress

Show simple item record

dc.contributor.author El-Deeb, W.M.
dc.date.accessioned 2022-06-17T16:00:17Z
dc.date.available 2022-06-17T16:00:17Z
dc.date.issued 2009-12-18
dc.identifier.citation W.M. El-Deeb. 2010. “Ascorbate-glutathion affiliation and the treatment of nutritional muscular dystrophy in lambs with special reference to the oxidative stress”. Cercetări Agronomice în Moldova 43 (2): 77-86. en_US
dc.identifier.uri https://repository.uaiasi.ro/xmlui/handle/20.500.12811/2540
dc.description.abstract This study was applied on a total number of 40 native breed lambs from Dakahlia governorate, their ages being ranged from 5 to 26 days, in order to declare the effects of nutritional muscular dystrophy as an oxidative stress in lambs and the effect of vitamin C administration in enhancing the treatment of Nutritional Muscular Dystrophy (NMD), decreasing oxidative stress and their correlation with glutathione in diseased lambs. The used lambs were allotted into four groups. Group 1 included apparently clinically healthy animals (n-10) and was the control group. The 2nd group (suffering from NMD) was treated by Vitamin E–selenium alone (n-10). The 3rd group (suffering from NMD) was treated by vitamin E –selenium and vitamin C (n-10) and the 4th group (suffering from NMD) was treated by vitamin C only (n-10). Two blood samples were obtained from each lamb, before and after treatment, and subjected to the laboratory investigation. The results revealed that there was significant increase in the oxidative stress markers with significant reduction in the antioxidant levels of diseased lambs. After the treatment, there were improvement of the general health condition and disappearance of the clinical signs within 4-7 days in group 2 and group 3, in contrast with the 4th group in which the clinical signs persisted even after treatment. The obtained results concerning blood and serum biochemical analysis revealed that NMD was playing an important role as an oxidative stressor in lambs. Moreover, antioxidant mixture of vitamin E-selenium and ascorbate proved to be more powerful and effective in the treatment of diseased lambs with NMD and decreasing the resulted oxidative stress. en_US
dc.language.iso en en_US
dc.publisher "Ion Ionescu de la Brad" University of Agricultural Sciences and Veterinary Medicine, Iași en_US
dc.subject lambs en_US
dc.subject Vitamin C, en_US
dc.subject NMD en_US
dc.subject oxidative stress en_US
dc.subject antioxidants en_US
dc.subject miei en_US
dc.subject vitamina C en_US
dc.subject miodistrofie nutriţională en_US
dc.subject stres oxidativ en_US
dc.subject antioxidanţi en_US
dc.title Ascorbate-glutathion affiliation and the treatment of nutritional muscular dystrophy in lambs with special reference to the oxidative stress en_US
dc.type Article en_US
dc.author.affiliation W.M. El-Deeb, Department of Internal Medicine and Infectious Diseases, Mansoura University, Egypt
dc.publicationName Cercetări Agronomice în Moldova
dc.volume 43
dc.issue 2
dc.publicationDate 2010
dc.startingPage 77
dc.endingPage 86
dc.identifier.eissn 2067-1865


Files in this item

This item appears in the following Collection(s)

Show simple item record