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Studies on the toxic effect of various pharmaceutical preparations obtained from Hamamelis virginiana

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dc.contributor.author Prisacaru, Cornelia
dc.contributor.author Prisăcaru, Anca-Irina
dc.date.accessioned 2022-06-15T06:40:23Z
dc.date.available 2022-06-15T06:40:23Z
dc.date.issued 2015
dc.identifier.citation Prisacaru Cornelia, Anca Irina Prisacaru. 2015. "Studies on the toxic effect of various pharmaceutical preparations obtained from Hamamelis virginiana." Lucrări Știinţifice USAMV – Iași Seria Horticultură, 58(1) : 293-298.
dc.identifier.issn 2069-8275
dc.identifier.uri https://repository.uaiasi.ro/xmlui/handle/20.500.12811/2525
dc.description.abstract Hamamelis virginiana L. (witch-hazel) is a shrub from Hamamelidaceae family cultivated in Europe for medical purposes. Due to its high tannins content (gallotannins, polycatechins, non-esterified gallic acid, procyanidins), flavonosides and safrole-rich volatile oil, Hamamelidis folium and Hamamelidis cortex extracts are part of many pharmaceutical products for internal and external use. Aqua Hamamelidis is one of the favourite preparations in cosmetics and dentistry. The experiment presented in this study focuses on monitoring the hepatotoxic effects of pharmaceutical products and aqueous extractive solutions from Hamamelidis folium and Hamamelidis cortex. The trial was conducted on four groups of Wistar rats, to which various pharmaceutical preparations from vegetal products of Hamamelis were administered internally. At the end of the four weeks trial, it was noticed that the biochemical parameters important for the hepatic function and integrity were modified. The hepatotoxic effects are particularly important for the preparations obtained from Hamamelidis cortex. en_US
dc.language.iso en en_US
dc.publisher “Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine, Iași en_US
dc.subject Hamamelidis folium en_US
dc.subject Hamamelidis cortex en_US
dc.subject Hamamelidis oil en_US
dc.subject hepatotoxicity en_US
dc.subject ulei de Hamamelis en_US
dc.subject hepatotoxicitate en_US
dc.title Studies on the toxic effect of various pharmaceutical preparations obtained from Hamamelis virginiana en_US
dc.title.alternative Studii privind efectele toxice ale unor preparate farmaceutice obtinute din Hamamelis virginiana en_US
dc.type Article en_US
dc.author.affiliation C. Prisacaru, University of Agricultural Sciences and Veterinary Medicine of Iasi, Romania
dc.author.affiliation A. I. Prisacaru, S.C. Fiterman Pharma, Iasi, Romania
dc.publicationName Lucrări Știinţifice USAMV – Iași Seria Horticultură
dc.volume 58
dc.issue 1
dc.publicationDate 2015
dc.startingPage 293
dc.endingPage 298


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