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Effect of selenium supplementation on serum amylase, lactate dehydrogenase and alkaline phosphatase activities in rats exposed to cadmium or lead

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dc.contributor.author Șlencu, Bogdan-Gabriel
dc.contributor.author Ciobanu, Constantin
dc.contributor.author Solcan, Carmen
dc.contributor.author Anton, Alina
dc.contributor.author Ciobanu, Stelian
dc.contributor.author Solcan, Gheorghe
dc.contributor.author Cuciureanu, Rodica
dc.date.accessioned 2021-07-15T11:40:12Z
dc.date.available 2021-07-15T11:40:12Z
dc.date.issued 2014-05-13
dc.identifier.citation Şlencu, B.G., C. Ciobanu, Carmen Solcan, Alina Anton, St. Ciobanu, Gh. Solcan, Rodica Cuciureanu. 2014. ”Effect of selenium supplementation on serum amylase, lactate dehydrogenase and alkaline phosphatase activities in rats exposed to cadmium or lead”. Cercetări Agronomice în Moldova 47 (4): 113-121. en_US
dc.identifier.uri https://repository.uaiasi.ro/xmlui/handle/20.500.12811/1760
dc.description.abstract The purpose of the study was to assess the effect of selenium supplementation on serum amylase, lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) activities in rats, during subacute exposure to toxic doses of cadmium or lead through the drinking water. The experimental groups (n=6) were: Control, Se (Se+4: 0,2 mg/l), Cd (Cd+2: 150 mg/l), Pb (Pb+2: 300 mg/l), Cd+Se (Cd+2: 150 mg/l; Se+4: 0,2 mg/l) and Pb+Se (Pb+2: 300 mg/l; Se+4: 0,2 mg/l). The animals were sacrificed after 56 days. Amylase, LDH and ALP activities were determined from serum. Se and Pb treatments caused an increase in amylase and LDH activities, when compared to Control group while Cd caused an increase in amylase activity and a decrease in LDH and ALP activities. Cd+Se caused a decrease in amylase activity and an increase in LDH activity, when compared to Cd. Pb+Se caused a decrease in amylase activity in comparison to lead. Selenium supplementation alleviated cadmium or lead induced changes in serum amylase activity. Selenium, coadministered with cadmium, caused a marked increase in serum LDH activity, when compared to cadmium alone or Control group while practically it had no effect on lead induced changes in LDH activity. Cadmium and lead induced disturbances in serum ALP activity were not influenced by selenium supplementation. en_US
dc.language.iso en en_US
dc.publisher "Ion Ionescu de la Brad" University of Agricultural Sciences and Veterinary Medicine, Iași en_US
dc.subject Rats en_US
dc.subject Lead en_US
dc.subject Cadmium en_US
dc.subject Selenium en_US
dc.subject Blood serum enzyme en_US
dc.title Effect of selenium supplementation on serum amylase, lactate dehydrogenase and alkaline phosphatase activities in rats exposed to cadmium or lead en_US
dc.type Article en_US
dc.author.affiliation B.G. Şlencu, C. Ciobanu, Rodica Cuciureanu, Grigore T. Popa” University of Medicine and Pharmacy, School of Pharmacy, Iaşi, Romania
dc.author.affiliation Carmen Solcan, Alina Anton, St. Ciobanu, Gh. Solcan, “Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine, School of Veterinary Medicine, Iaşi, Romania
dc.publicationName Cercetări Agronomice în Moldova
dc.volume 47
dc.issue 4
dc.publicationDate 2014
dc.startingPage 113
dc.endingPage 121
dc.identifier.eissn 2067-1865


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