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Investigations on lymphocytes blastization mechanism as a result of stimulation with a specific antigen

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dc.contributor.author Golban, Rita
dc.contributor.author Carp-Cărare, Mihai
dc.contributor.author Rîmbu, Cristina
dc.contributor.author Guguianu, Eleonora
dc.contributor.author Carp-Cărare, Cătălin
dc.contributor.author Horhogea, Cristina
dc.contributor.author Cozma, Andreea-Paula
dc.date.accessioned 2021-07-07T05:58:36Z
dc.date.available 2021-07-07T05:58:36Z
dc.date.issued 2016
dc.identifier.citation Golban, Rita, Mihai Carp-Cărare, Cristina Rîmbu, Eleonora Guguianu, Cătălin Carp-Cărare, Cristina Horhogea, Andreea-Paula Cozma. 2016. "Investigations on lymphocytes blastization mechanism as a result of stimulation with a specific antigen". Lucrări Științifice USAMV-Iași Seria Medicină Veterinară 59 (3): 270-275. en_US
dc.identifier.uri https://repository.uaiasi.ro/xmlui/handle/20.500.12811/1586
dc.description.abstract In this scientific paper are reflected the results of the investigation on the lymphocytes blastization mechanism aspects as result of stimulation with anti-anthrax antigen and protein purified derivative. The aim of the scientific research was to study the lymphocytes blastization mechanism as a result of stimulation with a specific antigen in order to determine the immunity of the vaccinated and unvaccinated animals. The study was made on twenty bovines using the method of lymphoblastic transformation test. The evaluations take part of a preliminary study in order to identify the transformation process of lymphocytes in macrophages cells determined by nucleus and cytoplasm cells increasing. The obtained results reveal that the majority percentage of the macrophages at this stage of cultivation is determined by the reduced phagocytic activity. As a result of visualization the preparations, there were observed macrophages young cells without vacuoles, with basophilia in the cytoplasm and well-defined contours of nucleus. The lymphocytic stimulation intensity was evaluated by the percentage determination of the blasts from the population, procedure known as morphological method of evaluation the blasts transformation. The active transformations of the macrophages after revaccination of young animals constituted 15,5% of blasts, compared to control group, where the index of stimulation constituted 3,5%. en_US
dc.language.iso en en_US
dc.publisher ”Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine, Iași en_US
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject lymphoblasts en_US
dc.subject immune response en_US
dc.subject mitogenic activity en_US
dc.subject specific antigen en_US
dc.title Investigations on lymphocytes blastization mechanism as a result of stimulation with a specific antigen en_US
dc.type Article en_US
dc.author.affiliation Rita Golban, The State Agrarian University of Moldova, Chișinău
dc.author.affiliation Mihai Carp-Cărare, Cristina Rîmbu, , Eleonora Guguianu, Cătălin Carp-Cărare, Cristina Horhogea, Andreea-Paula Cozma, USAMV Iași Faculty of Veterinary Medicine, 8 Mihail Sadoveanu Alley
dc.publicationName Lucrări Științifice USAMV - Iași, Seria Medicină Veterinară
dc.volume 59
dc.issue 3
dc.publicationDate 2016
dc.startingPage 270
dc.endingPage 275
dc.identifier.eissn 2393-4603


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Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)