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Composite Materials Based on Gelatin and Iron Oxide Nanoparticles for MRI Accuracy

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dc.contributor.author Drobotă, Mioara
dc.contributor.author Vlad, Stelian
dc.contributor.author Grădinaru, Luiza-Mădălina
dc.contributor.author Bargan, Alexandra
dc.contributor.author Radu, Iulian
dc.contributor.author Butnaru, Maria
dc.contributor.author Rîmbu, Cristina-Mihaela
dc.contributor.author Ciobanu, Romeo-Cristian
dc.contributor.author Aflori, Magdalena
dc.date.accessioned 2023-05-17T07:59:57Z
dc.date.available 2023-05-17T07:59:57Z
dc.date.issued 2022-05-12
dc.identifier.citation Drobota, Mioara, Stelian Vlad, Luiza Madalina Gradinaru, Alexandra Bargan, Iulian Radu, Maria Butnaru, Cristina Mihaela Rîmbu, Romeo Cristian Ciobanu, and Magdalena Aflori. 2022. "Composite Materials Based on Gelatin and Iron Oxide Nanoparticles for MRI Accuracy" Materials 15, no. 10: 3479. https://doi.org/10.3390/ma15103479. en_US
dc.identifier.issn 1996-1944
dc.identifier.uri https://www.mdpi.com/1996-1944/15/10/3479
dc.identifier.uri https://repository.uaiasi.ro/xmlui/handle/20.500.12811/3228
dc.description.abstract The majority of recent studies have focused on obtaining MRI materials for internal use. However, this study focuses on a straightforward method for preparing gelatin-based materials with iron oxide nanoparticles (G–Fe2O3 and G–Fe3O4) for external use. The newly obtained materials must be precisely tuned to match the requirements and usage situation because they will be in close touch with human/animal skin. The biocompatible structures formed by gelatin, tannic acid, and iron oxide nanoparticles were investigated by using FTIR spectroscopy, SEM-EDAX analysis, and contact angle methods. The physico-chemical properties were obtained by using mechanical investigations, dynamic vapor sorption analysis, and bulk magnetic determination. The size and shape of iron oxide nanoparticles dictates the magnetic behavior of the gelatin-based samples. The magnetization curves revealed a typical S-shaped superparamagnetic behavior which is evidence of improved MRI image accuracy. In addition, the MTT assay was used to demonstrate the non-toxicity of the samples, and the antibacterial test confirmed satisfactory findings for all G-based materials. en_US
dc.language.iso en en_US
dc.publisher MDPI en_US
dc.rights CC BY 4.0
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject antibacterial activity en_US
dc.subject magnetic determination en_US
dc.subject dynamic vapor sorption analysis en_US
dc.subject tensile propertiesy en_US
dc.subject gelatin en_US
dc.subject iron oxide en_US
dc.title Composite Materials Based on Gelatin and Iron Oxide Nanoparticles for MRI Accuracy en_US
dc.type Article en_US
dc.author.affiliation Mioara Drobota, Stelian Vlad, Luiza Madalina Gradinaru, Alexandra Bargan, Maria Butnaru, Magdalena Aflori, “Petru Poni” Institute of Macromolecular Chemistry, Aleea Gr. GhicaVoda, 41A, 700487 Iasi, Romania
dc.author.affiliation Iulian Radu, Department of Surgery, Regional Institute of Oncology, I-st Surgical Oncology, “Grigore T. Popa” University of Medicine and Pharmacy, 700483 Iasi, Romania
dc.author.affiliation Maria Butnaru, Department of Biomedical Sciences, “Grigore T. Popa” University of Medicine and Pharmacy, Kogalniceanu Street, 9-13, 700115 Iasi, Romania
dc.author.affiliation Cristina Mihaela Rîmbu, Department of Public Health, Faculty of Veterinary Medicine, “Ion Ionescu de la Brad” University of Life Sciences, Mihail Sadoveanu Alley no. 8, 700490 Iasi, Romania
dc.author.affiliation Romeo Cristian Ciobanu, SC All Green SRL, I. Bacalu Street, 5, 700029 Iasi, Romania
dc.author.affiliation Romeo Cristian Ciobanu, Electrical Engineering Faculty, “Gheorghe Asachi” Technical University of Iasi, Dimitrie Mangeron Bd., 67, 700050 Iasi, Romania
dc.publicationName Materials
dc.volume 15
dc.issue 10
dc.publicationDate 2022
dc.identifier.doi https://doi.org/10.3390/ma15103479


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CC BY 4.0 Except where otherwise noted, this item's license is described as CC BY 4.0