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Common European origin of Hepatitis E virus in human population from Eastern Romania

Show simple item record Porea, Daniela Aniță, Adriana-Elena Vâță, Andrei Teodor, Dănuț Crivei, Luciana-Alexandra Răileanu, Cristian Gotu, Vasilică Rățoi, Ioana-Alexandra Cozma, Andreea-Paula Aniță, Dragoș-Constantin Ludu Oșlobanu, Luanda-Elena Pavio, Nicole Savuța, Gheorghe 2023-03-10T07:25:30Z 2023-03-10T07:25:30Z 2020-12-17
dc.identifier.citation Daniela Porea, Adriana Anita, Andrei Vata et al. 2020. "Common European origin of Hepatitis E virus in human population from Eastern Romania". Frontiers in Public Health, 8.
dc.description.abstract The purpose of this research was to improve the epidemiological data on HEV infection in the human population in Romania. The analysis targeted hospitalized subjects with acute hepatitis (n = 94) of unknown etiology from the Infectious Diseases Regional Hospital in Iasi. Moreover, patients without liver disease (n = 40) from a different county hospital located in Eastern Romania were included. The presence of HEV infection and first characterization of human HEV strains was determined using serological and molecular assays. The apparent HEV seroprevalence varied between 29.16% (95% CI, 16.31–42.03) and 32.5% (95% CI, 17.98–47.02) according to patient grouping. Molecular analysis enhanced the detection of two HEV isolates, that clustered in subtype HEV-3c, the most commonly identified subtype in Europe. Identification of acute hepatitis E cases, together with the first detection and molecular characterization of human HEV in Romania represent the originality attributes of the present study. en_US
dc.language.iso en en_US
dc.publisher Frontiers Media en_US
dc.rights CC BY 4.0
dc.subject zoonotic character
dc.subject acute hepatitis
dc.subject hepatitis E virus
dc.subject phylogenetic analysis
dc.title Common European origin of Hepatitis E virus in human population from Eastern Romania en_US
dc.type Article en_US Daniela Porea, Adriana Anita, Luciana Crivei, Cristian Raileanu,Ioana Ratoi, Andreea Cozma, Dragos Anita, Luanda Oslobanu, Gheorghe Savuta, Department of Public Health, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Iasi, Iasi, Romania, Daniela Porea, Center for the Study of Transborder and Emergent Diseases and Zoonoses Department, Danube Delta National Institute for Research and Development, Tulcea, Romania Andrei Vata, Danut Teodor, Sfanta Parascheva” Infectious Diseases Hospital of Iasi, Iasi, Romania Cristian Raileanu, Laboratory of Vector Capacity, Institute of Infectology, Friedrich-Loeffler-Institut, Greifswald, Germany Vasilica Gotu, Department of Parasitology and Parasitic Diseases and Animal Biology, Faculty of Veterinary Medicine, University of Agronomical Sciences and Veterinary Medicine of Bucharest, Bucharest, Romania, Nicole Pavio, UMR Virologie 1161, ENVA, INRAE, Anses, Maisons-Alfort, France
dc.publicationName Frontiers in Public Health
dc.volume 8
dc.publicationDate 2020
dc.identifier.eissn 2296-2565
dc.identifier.doi 10.3389/fpubh.2020.578163

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CC BY 4.0 Except where otherwise noted, this item's license is described as CC BY 4.0